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My six-year-old and I went for a girls' outing to see this at the dollar theater. It is PG, so I hoped it'd be appropriate for her. She loved the book when we listened to it on CD.
Anyway, overall I thought the film was enjoyable. Zoie said she liked it and wasn't scared (there are quite a few Greek monsters).
Some of the things that were changed from the book didn't really seem great for a six-year-old though. The characters were older than they were in the book (Percy is 12 in the book, but seemed 16 or so in the movie). Thus, there were hormones. I don't recall the book having Hades' wife, but the film had her (quite skankily dressed). I also don't remember any swearing in the book, but the film had some.
I was bothered by the character Annabeth not being blonde. Seems like hair color is something you can easily follow.
There were quite a few other changes from the book, but on the whole, I thought the story was still told well.